Protein name:
Proprotein convertase subtilisin/kexin type 9 ;
Alternative:
Proprotein convertase 9 (PC9) ;Neural apoptosis-regulated convertase 1 (NARC-1) ;Subtilisin/kexin-like protease PC9 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
The precursor protein but not the mature protein may form multimers.
Function:
May play a role in cholesterol homeostasis (By similarity). May be implicated in the differentiation of cortical neurons and also in hepatic cells proliferation.
Subcellular Location:
Secreted
Protein Attributes:
50:
MGIRCSTWLR | WPLSPQLLLL | LLLCPTGSRA | QDEDGDYEEL | MLALPSQEDS |
100:
LVDEASHVAT | ATFRRCSKEA | WRLPGTYVVV | LMEETQRLQV | EQTAHRLQTW |
150:
AARRGYVIKV | LHVFYDLFPG | FLVKMSSDLL | GLALKLPHVE | YIEEDSLVFA |
200:
QSIPWNLERI | IPAWQQTEED | SSPDGSSQVE | VYLLDTSIQS | GHREIEGRVT |
250:
ITDFNSVPEE | DGTRFHRQAS | KCDSHGTHLA | GVVSGRDAGV | AKGTSLHSLR |
300:
VLNCQGKGTV | SGTLIGLEFI | RKSQLIQPSG | PLVVLLPLAG | GYSRILNTAC |
350:
QRLARTGVVL | VAAAGNFRDD | ACLYSPASAP | EVITVGATNA | QDQPVTLGTL |
400:
GTNFGRCVDL | FAPGKDIIGA | SSDCSTCYMS | QSGTSQAAAH | VAGIVAMMLN |
450:
RDPALTLAEL | RQRLILFSTK | DVINMAWFPE | DQRVLTPNRV | ATLPPSTQET |
500:
GGQLLCRTVW | SAHSGPTRTA | TATARCAPEE | ELLSCSSFSR | SGRRRGDRIE |
550:
AIGGQQVCKA | LNAFGGEGVY | AVARCCLLPR | VNCSIHNTPA | ARAGPQTPVH |
600:
CHQKDHVLTG | CSFHWEVENL | RAQQQPLLRS | RHQPGQCVGH | QEASVHASCC |
650:
HAPGLECKIK | EHGIAGPAEQ | VTVACEAGWT | LTGCNVLPGA | SLPLGAYSVD |
691:
NVCVARIRDA | GRADRTSEEA | TVAAAICCRS | RPSAKASWVH | Q
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Proprotein convertase subtilisin/kexin type 9
ELISA Kit for Rat Proprotein convertase subtilisin/kexin type 9
ELISA Kit for Rat Proprotein convertase subtilisin/kexin type 9
CLIA Kit for Rat Proprotein convertase subtilisin/kexin type 9
CLIA Kit for Rat Proprotein convertase subtilisin/kexin type 9
CLIA Kit for Rat Proprotein convertase subtilisin/kexin type 9
Polyclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Polyclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Polyclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Monoclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Monoclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Monoclonal Antibody for Rat Proprotein convertase subtilisin/kexin type 9
Protein for Rat Proprotein convertase subtilisin/kexin type 9
Protein for Rat Proprotein convertase subtilisin/kexin type 9
Protein for Rat Proprotein convertase subtilisin/kexin type 9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION
5.
"Functional characterization of Narc 1, a novel proteinase related to proteinase K."
Naureckiene S.
,
Ma L.
,
Sreekumar K.
,
Purandare U.
,
Lo C.F.
,
Huang Y.
,
Chiang L.W.
,
Grenier J.M.
,
Ozenberger B.A.
,
Jacobsen J.S.
,
Kennedy J.D.
,
DiStefano P.S.
,
Wood A.
,
Bingham B.
Arch. Biochem. Biophys.420:55-67(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION;AUTOCATALYTIC CLEAVAGE SITE;MUTAGENESIS OF GLN-151; SER-152; HIS-225 AND SER-385